Breathing Improvement Study for Heart Failure and Obesity
Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF
- Age
- 55 – 90
- Sex
- Any
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 78 (estimated)
- Sponsor
- University of Texas Southwestern Medical Center · Other
This trial is looking for people with heart failure and obesity to see how breathing problems affect their ability to exercise. Participants will help researchers understand the link between breathing and exercise capacity.
You may be able to join if
- I have signs and symptoms of heart failure
- I have an ejection fraction greater than 0.50
- I have objective evidence of diastolic dysfunction or elevated biomarkers
- I have been hospitalized for heart failure
- I am a healthy volunteer
You may not be able to join if
- I am younger than 55 years old
- I have a BMI over 50 kg/m2
- I have atrial fibrillation with poorly controlled heart rate
- I use phosphodiesterase type 5 (PDE5) inhibitors
- I have severe valvular disease
- I have severe chronic obstructive pulmonary disease (COPD)
- I have chronic kidney disease stage 4 or higher
- I have any restrictions in my ability to walk or move
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your EligibilityThe overall purpose of this study is to investigate whether pulmonary limitations that increase the oxygen (O2) cost of breathing impact dyspnea on exertion (DOE) and peak exercise capacity in patients with HFpEF and obesity. As per investigator's hypothesis, obesity is likely a significant contributor to DOE and exercise intolerance in patients with HFpEF.
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