Fluid Challenges for Surgery in Cancer Patients
Fluid Challenge and Plasma Volume, During Surgery
Recruiting
Phase 4
Interventional Study
Colorectal Cancer
Urologic Cancer
Gynecologic Cancer
Colorectal Disorders
Benign Neoplasm
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 85
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 60 (estimated)
- Sponsor
- Joachim Zdolsek · Other
Who this trial is looking for
This trial is looking for patients undergoing laparoscopic abdominal surgery for various cancers. Participants will receive different types of fluid treatments during surgery to see how they affect blood volume.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 18 and 85 years old
- I can give written consent to participate
- I have a relevant contraceptive method or am menopausal or have a negative pregnancy test
- I have an ASA category of I to III
- I will have laparoscopic abdominal surgery lasting at least 90 minutes
You may not be able to join if
- I am younger than 18 or older than 85 years
- I have known cardiac failure
- I am allergic to albumin
- I have kidney failure
- I am pregnant or planning to become pregnant
- I have extracellular hyperhydration or hypervolemia
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
A short bolus infusion of fluid, called "fluid challenge" is commonly recommended for fluid treatment during longer surgery. However a prolonged increase of the blood volume is a prerequisite to recommend the technique. The purpose with the study is to examine the plasma expanding effect of three different fluid challenge strategies (acetated Ringers 4 ml/kg body weight, albumin 5% 4 ml/kg body we…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Written consent to participate in the study
* For women: relevant contraceptive, menopausal or a negative pregnancy test.
* ASA category I to III
* Laparoscopic abdominal surgery, with a duration of at least 90 minutes.
* 18 to 85 years
Exclusion Criteria:
* Patients with kn…
Contacts