Nicotinamide Riboside and Prevention of Cancer Therapy Related Cardiac Dysfunction in Breast Cancer Patients

Recruiting Phase 2 Interventional Study
Breast Cancer Metastatic Breast Cancer Cancer Therapy-Related Cardiac Dysfunction Cardiotoxicity Heart Failure
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Female
Trial phase
Phase 2
Study type
Interventional
Purpose
Prevention
Participants needed
60 (estimated)
Sponsor
University Hospital, Akershus · Other
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About This Trial
Breast cancer is the most common form of cancer in women. Modern breast cancer treatments have led to increased survival, but at the same time, increased risk for cardiotoxicity and development of heart failure. In this study, the investigators want to evaluate whether nicotinamide riboside can prevent cancer-related cardiac dysfunction in metastatic breast cancer patients scheduled for anthracycl…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Women with metastatic breast cancer (stage IV breast cancer) scheduled for anthracycline-containing chemotherapy * Eastern Cooperative Oncology Group performance status 0-2 Exclusion Criteria * Age \<18 years * Acute myocardial infarction within the last three months * Parti…
Contacts

Torbjørn Omland, MD, PhD

+47 40107050

torbjorn.omland@medisin.uio.no

CONTACT

Victoria Vinje, MD

+47 92033665

victoria.vinje@ahus.no

CONTACT