Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases
Recruiting
Observational Study
Neutrophil-mediated Inflammatory Dermatoses
Inflammatory Dermatoses
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 100
- Sex
- Any
- Study type
- Observational
- Participants needed
- 3,370 (estimated)
- Sponsor
- University Hospital, Basel, Switzerland · Other
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About This Trial
This study is to identify rare, disease-causing mutations of several rare neutrophil dermatoses. To identify associations between NMID and variants in the genome next generation sequencing, mainly whole exome sequencing, will be used. In a second approach the expression level of already known inflammatory proteins in skin samples will be investigated.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* written consent of the participating person
* diagnosis of a disease in the NMID form group or proband of the control group
Exclusion Criteria for patients:
* Missing informed consent if samples collected after 2014
* no diagnosis of NMID
Exclusion Criteria for healthy cont…
Contacts