Blood Thinner Use After Varicose Vein Treatment
THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE)
Recruiting
Phase 4
Interventional Study
Venous Thromboembolism
Varicose Veins
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 3,175 (estimated)
- Sponsor
- Imperial College London · Other
Who this trial is looking for
This trial is looking for adults who are scheduled to have a specific procedure for varicose veins. Participants will find out if taking medicine to prevent blood clots after the treatment is helpful.
Are You a Good Fit for This Trial?
You may be able to join if
- I am an adult over 18 years old
- I am scheduled for an endovenous treatment for varicose veins
- I will receive local anesthesia for the procedure
- The treatment method includes radiofrequency, laser, foam sclerotherapy, or cyanoacrylate glue
You may not be able to join if
- I have a condition that requires blood-thinning medication
- I have a personal or family history of blood clots
- I have a condition that makes me prone to blood clots
- I am a female who could become pregnant and have a positive pregnancy test
- I am allergic to heparin or blood thinners
- I have had heparin-induced thrombocytopenia
- I have bleeding disorders or active bleeding
- I have serious health problems like active cancer or severe kidney/liver issues
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Endovenous interventions are keyhole operations for varicose veins that are carried out from within the vein itself. Varicose veins are enlarged veins close to the surface of the skin. They are connected to the bigger deeper veins in the leg (known as deep veins). Because of this, operations to close the varicose veins can increase the chance of a blood clot forming in the deep veins. Blood clots …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adults (\>18 years)
* Scheduled to undergo endovenous intervention of truncal varicose veins under local anaesthesia
* Treatment technologies including radiofrequency, laser, mechanochemical, foam sclerotherapy and cyanoacrylate glue
Exclusion Criteria:
* Clinical indication…
Contacts