Nab-paclitaxel Versus Sb-taxanes As First-Line Treatment in Advanced Ovarian Cancer

Inclusion Criteria: 1. Epithelial ovarian cancer/tubal cancer/peritoneal cancer was diagnosed by histopathology or hydroexfoliation cytopathology of the chest and abdomen, and was classified as stage III-IV according to FIGO（International Federation of Gynecology and Obstetrics）stage 2. Physical condition Eastern Cooperative Oncology Group PS score: 0-2 points 3. Participants who had not participated in other drug clinical trials within 4 weeks prior to enrollment 4. Written informed consent 5. Expected survival ≥6 months 6. The disease met the criteria for Efficacy Evaluation of solid tumors (RECIST 1.1) 7. Be able to comply with outpatient treatment, laboratory monitoring, and necessary clinical visits during study participation. Exclusion Criteria: 1. Patients with low malignant potential ovarian tumors; 2. Other malignant tumors within the previous 5 years, except for cured cervical carcinoma in situ and non-melanoma skin cancer; 3. Patients who have previously received chemotherapy or radiotherapy for pelvic cavity; 4. Patients with central nervous system metastasis or peripheral neuropathy \> grade 1; 5. Patients with severe myelosuppression, severe liver dysfunction (Child's Class III), or renal dysfunction at the time of screening; 6. Severe cardiovascular disease: Grade Ⅱ or above myocardial ischemia or myocardial infarction, poorly controlled arrhythmias (including QTc interval ≥470 ms); According to NYHA（New York Heart Association） criteria, patients with grade Ⅲ to Ⅳ cardiac insufficiency or left ventricular ejection fraction (LVEF) \< 55% indicated by color Doppler ultrasonography; 7. Uncontrolled systemic infection requiring anti-infective treatment; 8. Arteriovenous thrombosis events occurring within 6 months before randomization, such as cardiovascular and cerebrovascular accidents (including temporary ischemic attack, cerebral hemorrhage, cerebral infarction, myocardial infarction), deep vein thrombosis and pulmonary embolism; 9. Patients who are allergic to the active ingredients or excipients of albumin paclitaxel and carboplatin for injection; 10. Pregnant or lactating women; 11. Those who were considered unsuitable for inclusion by the researchers.