No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
120 (estimated)
Sponsor
University of British Columbia · Other
Who this trial is looking for
This trial is looking for adults who need surgery for oral cavity disease. Participants will compare two methods of closing the surgical site after using tissue from their forearm.
Are You a Good Fit for This Trial?
You may be able to join if
I am 18 years old or older
I have oral cavity disease requiring surgery
You may not be able to join if
I have serious medical issues like metastatic cancer
I have a condition that affects both of my hands
I cannot complete post-operative questionnaires in English
I am pregnant or breastfeeding
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The radial forearm free flap (RFFF) is widely used in head and neck reconstruction. Its thinness, pliability, pedicle length, and vessel size are particularly suited for oropharyngeal and oral cavity reconstruction. Concerns about aesthetic and functional morbidity at the donor site have given rise to various techniques of closing the donor site, two of which are the split-thickness skin graft (ST…
The radial forearm free flap (RFFF) is widely used in head and neck reconstruction. Its thinness, pliability, pedicle length, and vessel size are particularly suited for oropharyngeal and oral cavity reconstruction. Concerns about aesthetic and functional morbidity at the donor site have given rise to various techniques of closing the donor site, two of which are the split-thickness skin graft (STSG), taken from the thigh, and the hatchet flap, which uses a local flap within the radial forearm. This RCT will determine whether retrospectively reported improvements to aesthetic and functional outcomes for STSG patients are greater compared to hatchet flap patients.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adults aged 18 or older
* Oral cavity disease (malignant or benign) requiring radial forearm free flap reconstruction
Exclusion Criteria:
* Serious medical comorbidities including metastatic disease or other contraindications to surgery
* Any pre-existing condition affecting…
Inclusion Criteria:
* Adults aged 18 or older
* Oral cavity disease (malignant or benign) requiring radial forearm free flap reconstruction
Exclusion Criteria:
* Serious medical comorbidities including metastatic disease or other contraindications to surgery
* Any pre-existing condition affecting the use of both hands, including previous major scars
* Unable or unwilling to complete post-operative questionnaires in English
* Pregnant or lactating women
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