Serplulimab Combined With FOLFIRI and Bevacizumab in the Treatment of Colon Cancer Peritoneal Metastases

Recruiting Phase 2 Interventional Study
Unresectable Colon Cancer Peritoneal Metastases PMMR/Ras/BRAF Wild-type
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 75
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
30 (estimated)
Sponsor
Second Affiliated Hospital, Zhejiang University, School of Medicine · Other
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About This Trial

Multicentric randomised trial. The goal of this clinical research study is to evaluate the efficacy and safety of serplulimab combined with FOLFIRI+bevacizumab in the treatment of pMMR/Ras/BRAF wild-type unresectable peritoneal metastasis of colon cancer.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * 1\. Colon cancer was confirmed by histology, and its gene detection was pMMR/MSS and RAS/BRAF wild-type. Imaging showed peritoneal metastasis. * 2\. Peritoneal metastatic carcinoma that could not reach CC0/1 was detected surgically. * 3\. Patients with the following general ch…
Contacts

Lifeng Sun

+86-0571-87783777

sunlifeng@zju.edu.cn

CONTACT