Oxygen Toxicity: Mechanisms in Humans
Recruiting
N/A
Interventional Study
Oxygen Toxicity
Hypercapnia
Seizures
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 45
- Sex
- Any
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 62 (estimated)
- Sponsor
- Duke University · Other
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About This Trial
The goal of this clinical trial is to learn about the mechanisms of oxygen toxicity in scuba divers. The main questions it aims to answer are:
* How does the training of respiratory muscles affect oxygen toxicity?
* How do environmental factors, such as sleep deprivation, the ingestion of commonly utilized medications, and chronic exposure to carbon dioxide, impact the risk of oxygen toxicity?
* …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Equal numbers of male and female
* Non-smokers
* Aged 18-45 years
* Males will be required to have VO2 peak \> or equal to mL/kg min
* and females \> or equal to 30 mL/kg min
Exclusion Criteria:
* Pregnancy
* Cardiorespiratory disease, including hypertension
* Neuromuscular …
Contacts