Definition of Mutational Profile of Papillary Thyroid Tumors by Mass-ARRAY
Recruiting
Observational Study
Papillary Thyroid Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Sex
- Any
- Study type
- Observational
- Participants needed
- 600 (estimated)
- Sponsor
- Istituto Auxologico Italiano · Other
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About This Trial
Somatic mutations in the MAP (mitogen-activated protein) kinase pathway have been found in about 80% of papillary thyroid tumors (PTCs). The evaluation of the PTC mutational profile is crucial for the definition of the prognosis and for predicting the effects of targeted and personalized therapies. Molecular characterization by mass spectrometry (Mass ARRAY) allows the search for multiple mutation…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* patients with papillary thyroid cancer
* patients whose tumor tissue can be recovered for genetic analysis
Exclusion Criteria:
* patients who did not give consent
* patients lost to follow-up
* tumor samples not suitable for genetic analysis
Contacts