Effects of Intrauterine Administration of Autologous PBMC Modulated With IFNt on Endometrial Cell Populations

Recruiting N/A Interventional Study
Infertility
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 50
Sex
Female
Study type
Interventional
Purpose
Treatment
Participants needed
300 (estimated)
Sponsor
Nadezhda Women's Health Hospital · Other
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About This Trial
The aim of this clinical trial is to investigate the change in endometrial composition during the window of implantation following intrauterine administration of PBMC immunomodulated with IFNt. Patients seeking assisted reproductive therapy will be invited to participate. Two endometrial biopsies will be obtained from each patient during mid-secretory phase of two consecutive menstrual cycles. Th…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Participating in Assisted Reproduction Treatment * Having primary infertility * Having regular menstrual cycles * Having signed informed consent Exclusion Criteria: * Uterine pathologies * Endometrial bacterial infections * Active endometrial inflammation * Polycystic ovary …
Contacts

Dimitar Parvanov, PhD

885944618

dimparvanov@abv.bg

CONTACT