AV Junction Ablation for Atrial Fibrillation

AV Junction Ablation or Optimal Medical Treatment in PatiEnts With Cardiac Resynchronization Therapy and Permanent Atrial Fibrillation

Recruiting N/A Interventional Study
Recurrent Atrial Fibrillation Persistent Atrial Fibrillation
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 85
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
480 (estimated)
Sponsor
University Hospital Ostrava · Other
Who this trial is looking for

This trial is looking for patients with long-term atrial fibrillation who receive cardiac resynchronization therapy. Participants will either have a procedure to ablate a heart junction or continue with their current medication plan.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have been treated with cardiac resynchronization therapy for over 6 months
  • I have been diagnosed with permanent or recurrent persistent atrial fibrillation
  • I have needed emergency visits or hospital stays for my condition in the past year
  • I am on optimized heart failure medication and rate control medication
  • I am between 18 and 85 years old
  • I can provide signed informed consent

You may not be able to join if

  • I have had a heart attack or bypass surgery in the past 3 months
  • There was a technical failure with my cardiac resynchronization therapy system
  • I prefer to have my heart conduct signals naturally
  • My expected survival is less than 1 year
  • I have other serious health conditions that might interfere with the trial
  • I have dementia as assessed by a mini-mental test

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

A study comparing atrioventricular junction ablation (AVJA) versus continued optimum medical rate control in patients with cardiac resynchronization therapy (CRT) and atrial fibrillation (AF) with suboptimal heart rate control on optimum medication.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Treatment with CRT using either a biventricular pacemaker/defibrillator or conduction system pacemaker (\>6 months) * Diagnosis of AF and classified as: permanent AF or recurrent persistent AF, requiring emergency visits and/or hospitalizations (at least one in recent year) * …
Contacts

Jiří Hynčica

0042059737

jiri.hyncica@fno.cz

CONTACT