mpMRI for Muscle-invasive Bladder Cancer Diagnosis

Multi-parametric MRI in Patients Suspected for Muscle Invasive Bladder Cancer: a New Local Staging Paradigm

Recruiting N/A Interventional Study
Bladder Cancer Muscle-invasive Bladder Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Diagnostic
Participants needed
360 (estimated)
Sponsor
Radboud University Medical Center · Other
Who this trial is looking for

This trial is looking for patients suspected of having muscle-invasive bladder cancer. Participants will receive standard treatment and may also undergo a special MRI followed by a biopsy on the same day to help with diagnosis.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am at least 18 years old
  • I have a suspicion of muscle-invasive bladder cancer
  • I have no lymph node or distant metastases
  • I can provide written informed consent

You may not be able to join if

  • I am unable or unwilling to undergo an mpMRI
  • I am not fit for TURBT
  • I am not fit for definitive treatment with curative intent
  • I have a history of cancer, except for non-melanoma skin cancer, prostate cancer on active surveillance, or a solid tumor that has been disease-free for 5 years

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

A two-arm multicenter randomised controlled trial, comparing progression free survival, time to definitive treatment and cost-effectiveness of the standard of care (TURBT) and mpMRI followed by same-day cystoscopic bladder biopsy for diagnosis of patients with suspicion of muscle-invasive bladder cancer.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients (18+ years of age) * Clinically suspected MIBC * No lymph node or distant metastases * Written informed consent Exclusion Criteria: * Unable or unwilling to undergo mpMRI * Unfit for TURBT * Unfit for definitive treatment with curative intent * A history of cancer, …
Contacts

A. G. van der Heijden, Dr.

+31 (0)24 361 37 35

toine.vanderheijden@radboudumc.nl

CONTACT