Plaque Reversal With Early, Aggressive Lipid Lowering Therapy
Recruiting
Observational Study
Coronary Artery Disease Progression
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 50
- Sex
- Any
- Study type
- Observational
- Participants needed
- 60 (estimated)
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Other
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About This Trial
This study evaluates whether plaques in young patients with familial hypercholesterolemia (aged below 50 years) are susceptible to significant plaque regression with early, intensive lipid lowering therapy.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Diagnosed with heterozygous familial hypercholesterolemia
* Adult between 18 and 50 years old
* LDL cholesterol levels above 100 mg/dl (\>2.6 mmol/L) at inclusion
Exclusion Criteria:
* Renal insufficiency, defined as eGFR \< 30 ml/min
* History of atherosclerotic cardiovascu…
Contacts