Can Dapagliflozin Preserve Structure and Function in Transplanted Kidneys?

Recruiting Phase 4 Interventional Study
Kidney Transplant; Complications Kidney Transplant Failure Renal Failure
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 75
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Prevention
Participants needed
330 (estimated)
Sponsor
Oslo University Hospital · Other
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About This Trial
The goal of this clinical trial is to look at the effect of SGLT2 (Sodium glucose transporter 2) inhibition in patients receiving a kidney-transplant 6 weeks earlier at Oslo University hospital. Rikshospitalet. Investigators will search for answers along three pathways: Can SGLT2 inhibitor 1) preserve glomerular filtration rate (GFR), 2) reduce interstitial fibrosis in the kidney, and 3) favorably…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Renal transplant recipients transplanted 6 weeks earlier at Oslo University hospital (OUH) Rikshospitalet. * Age 18-75 years. * Able to comply with the medical treatment on their own. * Calcineurin inhibitor trough concentrations in accordance with individual therapeutic range…
Contacts

Trond Geir Jenssen, MD

0047 23073646

tjenssen@ous-hf.no

CONTACT

Charlotte Kongerud, MD

004723071917

ingkon@ous-hf.no

CONTACT