Mechanisms Underlying Efficacy of Prolonged Exposure

Recruiting N/A Interventional Study
Post Traumatic Stress Disorder
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
50 (estimated)
Sponsor
Massachusetts General Hospital · Other
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About This Trial
The primary objective of this research is to collect pilot data that demonstrates that proposed neural, psychophysiological and subjective markers measured before, during, and after treatment change over the course of Prolonged Exposure therapy (PE) for posttraumatic stress disorder (PTSD). The aims of the study are to: (1) examine theoretically informed mechanisms as pretreatment predictors of PE…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Age 18 or older 2. Meeting diagnostic criteria for PTSD as defined by DSM-5 assessed by the Diagnostic Interview for Anxiety, Mood, and Obsessive-compulsive and related Psychiatric Disorders (DIAMOND), and 3. Interest in starting PE Exclusion Criteria: 1. Current or past hi…
Contacts

Amanda W Baker, Ph.D.

617-643-6703

AWBAKER1@PARTNERS.ORG

CONTACT

Vladimir Ivkovic, Ph.D.

617-724-5550

VIVKOVIC@mgh.harvard.edu

CONTACT