Urine Testing for Non-muscle Invasive Bladder Cancer

Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance

Recruiting Phase 2 Interventional Study
Non-muscle-invasive Bladder Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Health Services Research
Participants needed
240 (estimated)
Sponsor
White River Junction Veterans Affairs Medical Center · Federal
Who this trial is looking for

This trial is looking for adults with a history of low-grade non-muscle invasive bladder cancer. Participants will help researchers see if urine tests can replace some bladder checks that are usually done with a scope.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am 18 years or older
  • I have low-grade intermediate-risk non-muscle invasive bladder cancer
  • I am willing to follow all study procedures
  • I have no signs of cancer recurrence within the last 6 months
  • I can understand and give consent in English or Spanish

You may not be able to join if

  • I have had my bladder completely removed
  • I have had a urinary diversion
  • I have a history of muscle-invasive bladder cancer
  • I am pregnant or breastfeeding
  • I have had urothelial carcinoma of the ureter or renal pelvis with recurrent disease
  • I have anatomical issues that make cystoscopy impossible
  • I cannot provide a urine sample

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
The purpose of this research is to determine whether bladder cancer monitoring can be improved by replacing some cystoscopy procedures with urine testing. Specifically, this study examines whether there are any differences in urinary symptoms, discomfort, number of invasive procedures, anxiety, complications, cancer recurrence or cancer progression when some cystoscopy procedures are replaced with…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Aged 18 years or older 2. History of low grade intermediate-risk non-muscle invasive bladder cancer, defined as most recent pathology report showing any of the following: * multifocal low grade non-invasive urothelial carcinoma of any size * solitary low grade non-inva…
Contacts

Prabhavathi Loganathan, MS

802-295-9363

Prabhavath.Loganathan@va.gov

CONTACT

Laura Jensen, MPH

802-280-5298

Laura.Jensen@va.gov

CONTACT