Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)

Recruiting Observational Study
Pleural Effusion Heart Failure Malignant Neoplasm Fluid Overload Hypoalbuminemia Renal Failure Cirrhosis Infections
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
120 (estimated)
Sponsor
Chinese University of Hong Kong · Other
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About This Trial

To assess the discriminative properties of pleural fluid (PF) N-terminal-proB-type-natriuretic-peptide (NTproBNP) levels in identifying heart failure (HF)-associated pleural effusions (PE).

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients hospitalized for heart failure and pleural effusion * Pleural tapping indicated for pleural fluid analysis. * Aged 18 years old or above Exclusion Criteria: * History of intrapleural therapy (including talc and fibrinolytic) in the ipsilateral pleural space. * Histo…
Contacts

Christopher Chan, MBChB

35053396

christopherchan@cuhk.edu.hk

CONTACT

Ken KP Chan, MBChB

35053396

chankapang@cuhk.edu.hk

CONTACT