The Value of Molecular Residual Disease Monitoring Based on ctDNA in Borderline Resectable or Locally Advanced Pancreatic Cancer
Recruiting
N/A
Interventional Study
Pancreatic Cancer
Locally Advanced
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 100 (estimated)
- Sponsor
- Peking Union Medical College Hospital · Other
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About This Trial
The goal of this clinical trial is to explore the value of molecular residual disease (MRD) monitoring based on ctDNA in borderline resectable or locally advanced pancreatic cancer. The main questions it aims to answer are:
* prognostic value of baseline MRD;
* the role of MRD dynamic changes after treatment in guiding treatment. Peripheral blood derived from participants will be obtained for MRD…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* patients with histologically confirmed borderline resectable or locally advanced pancreatic cancer;
* conversion therapy was planned;
* both sexes, age ≥18 years old;
* ECOG performance status score ≤2;
* the expected survival time was ≥3 months.
Exclusion Criteria:
* a know…
Contacts