Ischemic Conditioning to Promote Microvascular Resiliency in Frail Individuals
Recruiting
Phase 2
Interventional Study
Aging
Fragility
Endothelial Dysfunction
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 65 – 85
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 60 (estimated)
- Sponsor
- Medical College of Wisconsin · Other
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About This Trial
The goal of this clinical trial is to see how small blood vessels respond to the stress of high intensity exercise, and if a safe and simple intervention called ischemic conditioning can protect blood vessels from the stress of exercise.
Participants will come in for 3 study visits and get home-based ischemic conditioning. At Study Visit 1, participants will be assessed for their frailty and phys…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Women and men ages 65-85 years of age
Exclusion Criteria:
* Myocardial infarction in last 6 months
* morbid obesity (BMI \>40)
* heart failure
* uncontrolled hypertension
* other condition that precludes high intensity exercise (ex, neurological disorder, acute systemic infe…
Contacts