Ebastine Versus Mebeverine in IBS Patients

Recruiting Phase 3 Interventional Study
IBS - Irritable Bowel Syndrome IBS
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 65
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
200 (estimated)
Sponsor
Guy Boeckxstaens · Other
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About This Trial
Multicenter randomized controlled clinical trial comparing ebastine and mebeverine as treatment of irritable bowel syndrome Trial rationale 1. To perform a randomized superiority trial comparing the clinical efficacy of ebastine and mebeverine 2. To evaluate the impact of treatment with ebastine compared to mebeverine on quality of life and quality-adjusted life years Primary objective To provi…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Voluntary written informed consent of the participant or their legally authorized representative has been obtained prior to any screening procedures 2. Patients fulfilling the Rome IV criteria for non-constipated IBS (IBS-C subtypes will be excluded) 3. No organic cause that …
Contacts

Koen Bellens, MSc.

+3216341943

koen.bellens@kuleuven.be

CONTACT