Response Profiles to High-concentration Capsaicin Desensitization in Patients with Peripheral Neuropathic Pain with or Without Allodynia: a Regional Multicenter Prospective Cohort

Inclusion Criteria: * Patient over 18 years of age on the day of inclusion * Patient who has been informed and has not expressed opposition to participating in the study, * Patient with peripheral neuropathic pain (whatever the etiology), defined by : * "Neuropathic Pain 4" score ("DN4" score) ≥ 4/10 * AND pain according to the numerical scale (EN) \> 4/10, * AND stable analgesic treatment for at least 1 month, * AND with or without mechanical allodynia according to the Quantitative Sensory Testing (QST) : Brush test (dynamic), Von Frey test (static) * AND with or without thermal allodynia to hot or cold as determined by a ROLLTEMP-II® (Rolltemp is a device designed for quick screening of temperature sensibility over large body areas). * Patient responding to an indication of desensitization to high concentration capsaicin concentration and not presenting any contra-indication. * Patient naïve of high concentration of Capsaicin on the concerned zone * Patient understanding French Non-inclusion Criteria: * Patient with pain related to complex regional pain syndrome (criteria not meeting the indication for capsaicin) * Patient with active cancer (underlying disease and treatments may modify pain perception), * Patient receiving or having received in the last 3 months Botulinum toxin A on the concerned area (this treatment of neuropathic pain may modulate the effect of capsaicin and disturb the demonstration of causality), * Patient with planned surgery within the next 12 months on the painful site (surgery may cause neuropathic damage and/or bias the pain assessment), * Patient included in an interventional research protocol, * Patient under guardianship or curators, * Patient under legal protection Exclusion Criteria: None