Open-Label Placebo for Acute Pain Relief
Boosting Open-Label Placebo Effects in Acute Induced Pain in Healthy Adults
Recruiting
N/A
Interventional Study
Acute Pain
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 141 (estimated)
- Sponsor
- University Hospital, Basel, Switzerland · Other
Who this trial is looking for
This trial is looking for healthy adults aged 18 to 65 years to study how an open-label placebo can help relieve acute pain. Participants will undergo a controlled pain simulation and receive a placebo treatment while their pain response is evaluated.
Are You a Good Fit for This Trial?
You may be able to join if
- I am a healthy adult aged 18 to 65
- I have a body mass index (BMI) between 18 and 25
- I can understand the study and pain rating system
- I can give my informed consent
You may not be able to join if
- I have participated in a previous open-label placebo study
- I regularly take medications that can affect pain sensation
- I have neuropathy
- I have chronic pain
- I have a neuromuscular disease
- I have a dermatological disease
- I have a psychiatric disease
- I am pregnant or breastfeeding
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
This study is to investigate the effect of open-label placebo (OLP) application on acute pain in an experimental model of acute pain (simulating wound pain: this installation will apply monophasic, rectangular electrical pulses of 0.5ms duration with alternating polarity at 2 Hz frequency. The current will be increased to target a pain rating of 6 of 10 on the NRS (0 = no pain, 10 = worst imaginab…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Healthy volunteers (ASA Class I or II), aged 18 to 65 years
* BMI between 18 and 25kg/m2
* Able to understand the study and the NRS
* Able to give informed consent
Exclusion Criteria:
* Participation in a previous open-label placebo study; for Part 2, this includes Part 1 of…
Contacts