Investigating Neural Biomarkers for Gait in Parkinson's Patients
Recruiting
Observational Study
Parkinson DiseaseGait Disorders, Neurologic
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
60 (estimated)
Sponsor
Swiss Federal Institute of Technology · Other
Who this trial is looking for
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
This observational study's main goal is to learn more about the neural mechanisms during movement in Parkinson's disease. Furthermore, it aims to inspire personalised treatment options.
Participants will undergo a protocol that involves walking and gait-related motor tasks, such as seated stepping. During the protocol, brain activity will be recorded.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
All participants
* must have given informed consent as documented by signature
* agree to comply with the study procedures
Healthy control group
* no neurological, orthopedic, or rheumatologic disease history
* no identified sensory impairment.
* no epilepsy and self-diagnose…
Inclusion Criteria:
All participants
* must have given informed consent as documented by signature
* agree to comply with the study procedures
Healthy control group
* no neurological, orthopedic, or rheumatologic disease history
* no identified sensory impairment.
* no epilepsy and self-diagnosed acute or chronic psychiatric disorders
Parkinson's Patients
* non-tremor dominant idiopathic PD patients
* presence of postural instability (UPDRS \>1 for postural instability \[17\]), gait disturbance, and absence of other causes of reduced balance
* Implanted with Percept™ PC neurostimulator
* Able to be in the stimulation OFF
Exclusion Criteria:
* Relevant cognitive impairment, with a score on Montréal Cognitive Assessment (MoCA) \< 20
* History of physical or neurological condition that interferes with study procedures
* Social and/or personal circumstances interfering with the ability to come to the session
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