Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery
Recruiting
Phase 4Interventional Study
Pain, Postoperative
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
120 (estimated)
Sponsor
Loyola University · Other
Who this trial is looking for
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The goal of this clinical trial is to learn if there is a difference in morphine requirements in patients after upper extremity surgeries including shoulder arthroscopy. The main question it aims to answer is whether there is a difference between Interscalene brachial plexus blocks with the addition of buprenorphine, dexamethasone, and clonidine and the same block without the adjuvant.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Patients ≥ 18 years old
* Patients undergoing shoulder arthroscopy
* Patients willing to participate and sign informed consent
Exclusion Criteria:
* Severe COPD/other contraindication to general anesthesia
* Patient with a weight of less than 60 kg
* Dementia, not alert or o…
Inclusion Criteria:
* Patients ≥ 18 years old
* Patients undergoing shoulder arthroscopy
* Patients willing to participate and sign informed consent
Exclusion Criteria:
* Severe COPD/other contraindication to general anesthesia
* Patient with a weight of less than 60 kg
* Dementia, not alert or oriented to person, place, or time
* Chronic pain patient with daily opioid use at home.
* Patient with allergy to local anesthetics
* Patient refusal
* Total shoulder arthroplasty
* Concomitant pain in different area from operative site.
* Pregnancy
* Patient with active infection on the injection sites for the blocks
* Patients unable or willing to understand or comply with the study protocol
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