Pulmonary Hypertension: Intensification and Personalisation of Combination Rx

Recruiting Phase 4 Interventional Study
Pulmonary Arterial Hypertension
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 80
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
40 (estimated)
Sponsor
Sheffield Teaching Hospitals NHS Foundation Trust · Other
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About This Trial
The goal of this clinical trial is to evaluate the capacity of implantable/remote technology for early evaluation of drug therapies in patients with pulmonary arterial hypertension (PAH). The main question it aims to answer is whether structured changes in clinical therapy will be detectable using implanted regulatory approved devices. Participants will will be implanted with approved medical devi…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Able to provide informed consent * Age 18-80 years * PAH which is idiopathic, heritable or associated with drugs, toxins or connective tissue disease * Stable PAH therapeutic regime comprising any combination of ERA and PDE5i for at least 1 month prior to screening (unless una…
Contacts

Shravya Rao

+44 (0) 114 2159550

s.rao@sheffield.ac.uk

CONTACT