Light Exposure Study for Sleep and Daily Rhythms
Impact of Sex and Age on Non-visual Light Input That Affects Sleep and Circadian Rhythms
Recruiting
N/A
Interventional Study
Normal Physiology
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 85
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 48 (estimated)
- Sponsor
- Massachusetts General Hospital · Other
Who this trial is looking for
This trial is looking for healthy people aged 18-85 to study how different light affects sleep and daily cycles. Participants will wear a watch to track their activity and light, and then stay in a research room for testing over three days and two nights.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 18 and 85 years old.
- I usually go to sleep between 10 pm and 1 am.
- I usually wake up between 5:30 am and 8:30 am.
- I can see well with my glasses if needed.
- I am stable medically.
- I can speak, read, and understand English at a high school level.
You may not be able to join if
- I am color blind.
- I have a history of eye problems or surgeries.
- I have or have had any neurological or psychiatric disease.
- I have current or past sleep-wake disorders.
- I take medications that affect my sleep or pupil response.
- I have health conditions like diabetes or Parkinson's disease.
- I have worked night shifts in the past three months.
- I am pregnant, less than 6 weeks post-partum, or breastfeeding.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The goal of this clinical trial is to learn how the pupil responds to different light stimuli and how that relates to sleep and daily rhythms in healthy people of different ages.
The main questions it aims to answer are:
* Does the eye's pupil response to light stimuli differ by the sex and age of the participant?
* Is the eye's pupil response to light stimuli related to each participant's sleep…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* (i) 18-85 years old.
* (ii) Habitual sleep onset 10 pm- 1 am (healthy controls only);
* (iii) Habitual wake onset 5:30 am- 8:30 am (healthy controls only);
* (iv) vision correctable to 20/30;
* (v) stable medically.
* (vi) ability to speak, understand, and read English at a hi…
Contacts