Pulmonary Immune Cell-microbiome Interactions in the Healthy Lung

Recruiting Observational Study
Healthy
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
40 – 75
Sex
Any
Study type
Observational
Participants needed
50 (estimated)
Sponsor
Hvidovre University Hospital · Other
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About This Trial
The overall aim is to to provide a normal material for the composition and spatial heterogeneity of the following in the healthy lung: i) immune cell populations and their activation patterns, ii) the surrounding cytokine-chemokine milieu, including trans-compartmental fluxes of these mediators between the lung and bloodstream, and iii) the lung microbiome. Main hypotheses: * Absolute and relati…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Men and women * Age 40 to 75 Exclusion Criteria: * Immune deficiency * Lung disease * Active cancer or infection * Absolute contraindications for bronchoscopy * Untreated malignant arrhythmia * Documented or suspected intracranial hypertension (intracranial pressure ≥ \…
Contacts

Ronni Plovsing, MD, PhD

+45386220721

ronni.thermann.reitz.plovsing.01@regionh.dk

CONTACT

Katrine Schneider, MD

+4528118147

katrine.schneider@regionh.dk

CONTACT