buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest
Recruiting
Phase 2
Interventional Study
Hypoxia-Ischemia, Brain
Heart Arrest
Status Epilepticus
Refractory Status Epilepticus
Seizures
Anoxic-Ischemic Encephalopathy
Anoxia-Ischemia, Cerebral
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 30 (estimated)
- Sponsor
- University of California, San Francisco · Other
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About This Trial
RESTORE is a randomized clinical trial investigating the safety and feasibility of using EEG treatment targets (burst suppression vs. seizure suppression) for post-cardiac arrest refractory status epilepticus treatment.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age ≥18 years old
2. Non-traumatic, out-of-hospital cardiac arrest
3. Comatose on admission - defined as not following commands
4. Return of spontaneous circulation (ROSC) within less than 45 minutes
5. Admission to the intensive care unit
6. Diagnosis of post-cardiac arrest …
Contacts