Circulating Biomarker Signatures for the Detection of Gastric Preneoplasia and Cancer
Recruiting
N/AInterventional Study
Gastric LesionGastric Precancerous ConditionGastric Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
2,500 (estimated)
Sponsor
Institut Pasteur · Industry
Who this trial is looking for
This trial is looking for people with certain stomach conditions and healthy volunteers. If you join, you'll provide a blood sample for research on gastric cancer risks.
Are You a Good Fit for This Trial?
You may be able to join if
I am 18 years old or older
I have given written consent to participate
I am enrolled in a social insurance system
I have untreated glandular atrophy or gastric cancer diagnosed since 2014
You may not be able to join if
I have an autoimmune disease or a condition affecting my immune system
I have chronic inflammation or a cancer other than gastric cancer
I have been treated in the last 3 months with immune-suppressing therapy
I am currently taking long-term corticosteroids or anti-inflammatory drugs
I am pregnant or breastfeeding
I am under legal protection
I am currently in another clinical trial
I have a known history of Helicobacter pylori infection or gastric lesions
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The goal of this study is to characterize and validate a signature of circulating biomarkers in plasma, associated with the presence of gastric preneoplasia in patients with preexisting gastric lesion compared with a control group.
For this purpose:
* Patients with pre-existing gastric lesions will be invited to participate to this study. If they are willing to participate an additional blood sa…
The goal of this study is to characterize and validate a signature of circulating biomarkers in plasma, associated with the presence of gastric preneoplasia in patients with preexisting gastric lesion compared with a control group.
For this purpose:
* Patients with pre-existing gastric lesions will be invited to participate to this study. If they are willing to participate an additional blood sample (9 mL) will be collected at the time of the blood collection performed during their routine care
* Healthy subjects will be invited to participate to constitute the control group. If they are willing to participate a blood sample (9 ml) will be drawn specifically for this study
Trial Locations
Loading…
Loading trial locations…
Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria:
Common
* 18 years old or highter
* written informed consent prior to any study procedure
* Affiliated to a social insurance system
Specific to patients with gastric lesions
* Untreated glandular atrophy (with or without intestinal metaplasia and/or dysplasia) and histological…
Inclusion Criteria:
Common
* 18 years old or highter
* written informed consent prior to any study procedure
* Affiliated to a social insurance system
Specific to patients with gastric lesions
* Untreated glandular atrophy (with or without intestinal metaplasia and/or dysplasia) and histologically diagnosed as of 2014
* Treatment naïve Gastric cancer (distal or proximal adenocarcinoma)
Exclusion Criteria:
Common
* Autoimmune disease or disease that impacts the immune system (e.g: HIV)
* Chronic inflammatory disease
* Known evolutive cancer (excluding gastric cancer)
* Treated in the last 3 months or currently treated with therapy that interferes with the immune system (e.g. immunosuppressive therapy)
* Current treatment with long-term corticosteroid therapy
* Current treatment with long-term nonsteroidal anti-inflammatory drugs
* Pregnant woman or breastfeeding
* Patient or healthy volunteer under legal protection (e.g. guardianship)
* Patient or healthy volunteer currently participating to a clinical trial evaluating either an experimental medical product or a medical device
* Patient or healthy volunteer currently in custody
Specific to Healthy Volunteer
* Known history of Helicobacter pylori infection
* Known history of gastric lesions (i.e. chronic gastritis, gastric atrophy, intestinal metaplasia, dysplasia and cancer)
Picking one helps us show the most relevant trials first.
Your results are loading in the background — you can
change this any time from the results page.
Set your location to continue
Find My Trials uses your location to surface clinical trials near you.
Add your city or zip code to your profile and try again.