A Study to Investigate of the Effects of Opioid Exposure on the Ability of the Diaphragm Muscle

Recruiting Phase 4 Interventional Study
Respiratory Function Loss Respiratory Complication
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Basic Science
Participants needed
69 (estimated)
Sponsor
Mayo Clinic · Other
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About This Trial

The purpose of this study is to evaluate opioid dose effects on the ability of the diaphragm muscle to generate higher force behaviors.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: \- Adult male and female patients undergoing lower extremity orthopedic surgery at the study institutions (St. Mary Hospital and Rochester Methodist Hospital within the Mayo Clinic Rochester hospital system). Exclusion Criteria: * Patients who refuse research participation. * …
Contacts

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