The ENHANCE Study: taVNS and Psilocybin
Recruiting
Phase 1
Interventional Study
Healthy
Psychedelic Experiences
Vagus Nerve Stimulation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 70
- Sex
- Any
- Trial phase
- Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 108 (estimated)
- Sponsor
- University of Wisconsin, Madison · Other
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
This study will examine whether combining a single dose of psilocybin with non-invasive transcutaneous auricular vagus nerve stimulation (taVNS), a potential inducer of neuroplasticity and enhanced memory formation, will enhance the long-term beneficial behavioral effects of psilocybin when compared to sham taVNS or no VNS by allowing memory for insights gained during the psychedelic experience to…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
* English speaking
* Ability/willingness to complete all study activities
* Modest reduction in emotional well-being
* Medically healthy (does not meet criteria for an exclusionary medical condition)
* Blood pressure and heart rate within established ranges at screening
* Use of…
Contacts