The Effect of Obesity and Weight Loss in Heart Failure With Preserved Ejection Fraction
Recruiting
N/A
Interventional Study
Heart Failure With Preserved Ejection Fraction
Obesity
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 85
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 120 (estimated)
- Sponsor
- University of Oxford · Other
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
This study looks at the effects of weight loss in people who have heart failure with preserved ejection fraction (HFpEF) and are overweight or obese.
The main questions it aims to answer are whether weight loss in this group of people improves:
1. The heart's shape, how well it pumps blood and how well it uses fuels
2. The person's quality of life and how much they can exercise
Participants wil…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
* Heart failure with preserved ejection fraction (HFpEF)
* Left ventricular ejection fraction (LVEF) =/\> 50%
* Body Mass Index (BMI) approximately =/\> 27.5 kg/m\^2
Exclusion Criteria:
* Contraindications to magnetic resonance imaging
* NYHA class IV
* Significant valvular, i…
Contacts