No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 49
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
72 (estimated)
Sponsor
Columbia University · Other
Who this trial is looking for
This trial is looking for young to middle-aged adults who sleep regularly and are interested in how variations in sleep might affect health. Participants will try different sleep schedules over a 4-week period.
Are You a Good Fit for This Trial?
Rules you outSleep disordersPsychiatric disordersPregnancyBreastfeedingDiabetesElevated blood pressureRecent weight changeShift work
You may be able to join if
I am aged 18 to 49 years
I have a BMI between 20 and 29.9
I usually sleep 7 to 9 hours a night without aids or naps
You may not be able to join if
I have a sleep disorder
I have a psychiatric disorder or seasonal affective disorder
I am pregnant or have been pregnant in the past year
I am breastfeeding
I smoke or have smoked within the last 3 years
I have diabetes
I have high blood pressure and take beta-blockers
I have taken blood thinners recently
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The goal of this clinical trial is to test the impact of repeated intermittent short sleep, with short sleep maintained 5 days per week followed by 2 days of prolonged sleep, compared to daily adequate sleep, on energy balance and cardiometabolic risk. A secondary goal of this research is to determine if maintaining a constant midpoint of sleep while undergoing intermittent short sleep, leads to b…
The goal of this clinical trial is to test the impact of repeated intermittent short sleep, with short sleep maintained 5 days per week followed by 2 days of prolonged sleep, compared to daily adequate sleep, on energy balance and cardiometabolic risk. A secondary goal of this research is to determine if maintaining a constant midpoint of sleep while undergoing intermittent short sleep, leads to better outcomes than intermittent short sleep with a 2-hour delay in sleep midpoint. The aims of this research will be tested in the context of a 3-group, parallel-arm, outpatient intervention of 4 weeks in duration, in young-to-middle-aged adults (aged 18-49 years).
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Aged 18 to 49 years
* BMI 20-29.9 kg/m2
* Habitually sleeping 7-9 hours/night without sleep aids or naps
Exclusion Criteria:
* Sleep disorders
* Psychiatric disorders (including eating disorders) and seasonal affective disorder
* Pregnancy (current/prior year)
* Breastfeedin…
Inclusion Criteria:
* Aged 18 to 49 years
* BMI 20-29.9 kg/m2
* Habitually sleeping 7-9 hours/night without sleep aids or naps
Exclusion Criteria:
* Sleep disorders
* Psychiatric disorders (including eating disorders) and seasonal affective disorder
* Pregnancy (current/prior year)
* Breastfeeding
* Smokers (Any cigarette smoking or ex-smokers \<3years)
* Diabetes
* Elevated blood pressure, taking beta-blockers
* Individuals taking anti-coagulants or anti-platelets
* Recent weight change or participation in a weight loss program or have ever had bariatric surgery or other weight loss or gastrointestinal procedure.
* Travel across time zones; shift work (non-traditional hours)
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