Confirming Permanent Lack of Blood Flow to the Brain During A-NRP DCC Organ Transplant

Recruiting Observational Study
Organ Transplant
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 75
Sex
Any
Study type
Observational
Participants needed
30 (estimated)
Sponsor
Western University, Canada · Other
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About This Trial
This study aims to evaluate the surgical technique used in Abdominal Normothermic Regional Perfusion (A-NRP) in death determination by circulatory criteria (DCC) organ donors. The proposed study will demonstrate that there is no resumption of brain blood flow or activity during the A-NRP procedure. This will be assessed using multimodal neuromonitoring protocol that enables continuous focused moni…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * ≤ 18 years of age * Potential DCC donors whose families/surrogate decision makers have consented to DCC organ donation according to current criteria of the participating transplant programs. These may include patients donating a liver, kidneys, pancreas, and/or lungs; please s…
Contacts

Crystal Engelage, PhD

519-685-8500

Crystal.Engelage@lhsc.on.ca

CONTACT

Anton Skaro, MD PhD

519-663-2904

Anton.Skaro@lhsc.on.ca

CONTACT