Investigation of the Clinical Efficacy of Low-dose Ionizing Radiation in the Treatment of Osteoarthritis

Inclusion Criteria: * Diagnosed osteoarthritis according to ACR criteria (exclusion of other other arthritides and chronic rheumatoid arthritis via laboratory tests): * Finger and wrist osteoarthritis * Elbow arthrosis * Shoulder arthrosis * Knee arthrosis * Ankle and foot joint arthrosis * First time application of low-dose radiotherapy (LDRT) of the affected joint. * Willingness to cooperate and accessibility of the patients (geographical proximity) for treatment and Follow-up care Exclusion Criteria: * Patients with tumor diseases * People capable of childbearing or procreation who do not take consistent contraceptive measures during therapy * Persistent drug, medication or alcohol abuse * Patients for whom, in the physician's judgment, participation is not justifiable with regard to their well-being due to temporary withdrawal of standard medication. * Patients in whom the diagnosis of osteoarthritis of the affected joint cannot be made without doubt. To establish the diagnosis, the guidelines of the American College of Rheumatology (ACR) are followed. * Earlier radiation therapy for treatment of cancer