Optimizing DBS Settings for Parkinson's Disease
Multiple Objective Particle Swarm Optimization Postural Instability Gait Disorder
Recruiting
Early Phase 1
Interventional Study
Parkinson Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 89
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 60 (estimated)
- Sponsor
- University of Minnesota · Other
Who this trial is looking for
This trial is looking for patients with Parkinson's disease who have had deep brain stimulation (DBS) surgery. Participants will have their brain scans used to create personalized settings for their neurostimulator to improve their movement and balance.
Are You a Good Fit for This Trial?
You may be able to join if
- I have been diagnosed with Parkinson's disease.
- I have had bilateral deep brain stimulation.
- I have a directional DBS electrode system.
- I had an MRI at least 7 Tesla before my DBS surgery.
- I had a head CT after my DBS surgery.
- At least 3 months have passed since my neurostimulator was activated.
You may not be able to join if
- I have a neurological or musculoskeletal disorder that affects my movement.
- I have dementia.
- I have had prior brain surgery other than DBS for movement disorder.
- I am pregnant.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Sixty patients will be enrolled in this study who are treated for Parkinson's disease (PD) with bilateral deep brain stimulation of subthalamic nucleus (STN) or globus pallidus (GP), who have a pre- operative 7 Tesla MRI including diffusion tensor imaging for tractography and a postoperative head CT for electrode localization, and in whom at least 3 months have passed since activation of their neu…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Diagnosis of PD
* Bilateral DBS
* Directional DBS electrode system
* MRI, at least 7 Tesla, with diffusion tensor imaging, prior to DBS surgery
* Head CT, at least 1mm cuts, following DBS surgery
* At least 3 months since initial activation of the neurostimulator
Exclusion Cr…
Contacts