MIcronized PROgesterone in Frozen Embryo Transfer Cycles

Recruiting Phase 3 Interventional Study
Infertility
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 50
Sex
Female
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
1,020 (estimated)
Sponsor
Fundación Santiago Dexeus Font · Other
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About This Trial
This randomized trial was designed as non-inferiority trial aiming to compare ongoing pregnancy rates following LPS with 600 mg/day vs 800 mg/day vaginal VMP. All patients will undergo an artificial cycle frozen embryo transfer (AC-FET) with transdermal estradiol 6mg/day Patients undergoing an artificial cycle FET will start estrogen priming with transdermal estradiol 6mg/day (Estrogel®) on cycle …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Endometrial preparation with hormone replacement therapy * Age 18-43 years following an autologous IVF cycle (with or without preimplantation genetic testing for aneuploidy) * Age \< 50 years following an egg donation cycle * BMI \> 18 and \< 30 kg/m2 * blastocyst embryo trans…
Contacts

Nikolaos P Polyzos, MD, PhD

0034932274700

nikpol@dexeus.com

CONTACT

Ignacio Rodríguez, MSc

0034932274700

nacrod@dexeus.com

CONTACT