Immune Function and the Progression to T1D
Recruiting
Observational Study
Type 1 Diabetes
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 0 – 100
- Sex
- Any
- Study type
- Observational
- Participants needed
- 2,800 (estimated)
- Sponsor
- University of Florida · Other
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About This Trial
To elucidate the mechanisms by which type 1 diabetes-associated genes; IFIH1, TYK2, IKZF4, as well as total genetic risk, impart functional immunoregulatory abnormalities that result in expansion of self-reactive adaptive immune cells, defective regulatory/effector mechanisms in T cells, inflammatory antigen presenting cells, and abnormal immune function in T cells and B cells.
Trial Locations
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Eligibility Criteria
Inclusion Criteria: able to have blood drawn -
Exclusion Criteria: none
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Contacts