Evaluating 111In Panitumumab for Nodal Staging in Head and Neck Cancer

Recruiting Phase 1 Interventional Study
Head and Neck Squamous Cell Carcinoma Recurrent Head and Neck Squamous Cell Carcinoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
19 and older
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
30 (estimated)
Sponsor
Vanderbilt-Ingram Cancer Center · Other
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About This Trial
This phase I trial tests the safety and effectiveness of indium In 111 panitumumab (111In-panitumumab) for identifying the first lymph nodes to which cancer has spread from the primary tumor (sentinel lymph nodes) in patients with head and neck squamous cell carcinoma (HNSCC) undergoing surgery. The most important factor for survival for many cancer types is the presence of cancer that has spread …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥ 19 years. * Biopsy-confirmed diagnosis of squamous cell carcinoma of the head and neck, clinically-staged as node-negative (cN0) or as clinically-suspicious node(s). * Subjects diagnosed with any T stage, any subsite within the head and neck that are scheduled to undergo…
Contacts

Nicole Jones

615-936-2807

nicole.l.jones@vumc.org

CONTACT