Total Neoadjuvant Treatment of Rectal Cancer by MRI-guided Radiotherapy

Recruiting Observational Study
Rectal Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
35 (estimated)
Sponsor
Universitair Ziekenhuis Brussel · Other
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About This Trial
The TNTRect trial is a prospective observational study that will evaluate the outcome of MR-guided stereotactic body radiotherapy (SBRT) with a simultaneous integrated boost in a hypofractionated treatment of rectum cancer. Patients will be treated in 5 daily fractions of 5 Gy within an overall treatment time (OTT) of 5 days. A simultaneous integrated boost (SIB) till 30Gy will be delivered to the…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Locally advanced rectal cancer Exclusion Criteria: * Patients with unresectable metastatic disease at diagnosis * Patients with an ECOG performance status \> 2 * Patients not deemed fit for radiotherapy, chemotherapy or surgery
Contacts

Mark De Ridder, MD

00324776041

mark.deridder@uzbrussel.be

CONTACT

Sven Van Laere, PhD

00324776041

sven.vanlaere@uzbrussel.be

CONTACT