Observational Study of Viral BIOmarkers and microRNAs in Tumors Orofarynx and Occult Tumors Positive for Papilloma Virus
Recruiting
Observational Study
Squamous Cell Carcinoma of the Oropharynx
Carcinomas of Unknown Primary Site
High-risk Human Papillomavirus Infection
Liquid Biopsy
Lymph Node Metastasis
Occult Tumor of the Head and Neck Area
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 142 (estimated)
- Sponsor
- Regina Elena Cancer Institute · Other
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About This Trial
Based on the evidence summarized in the introduction, the clinician hypothesize that the detection of the presence and expression of HPV-DNA, certain miRNAs, and a certain mutational profile in the tissues and biological fluids of these patients, may have important prognostic and diagnostic value not only in HPV-related OPSCCs but also in HPV+ occult T. Accordingly, this study aims to aim to bette…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Squamous cell carcinomas of the oropharynx and occult neoplasms with lymph node metastases laterocervical cytologically positive for squamous cell carcinoma treated with TORS or RT or RT/CT
* Age \> 18 years
* ECOG performance status \<\_ 2
* Ability to follow study procedures…
Contacts