Ferroptosis Study for Myelodysplastic Syndromes
Ferroptosis Study in SF3B1-mutant Myelodysplastic Syndromes (FerMDS)
Recruiting
N/A
Interventional Study
Myelodysplastic Syndromes
Ferroptosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 80 (estimated)
- Sponsor
- University Hospital, Bordeaux · Other
Who this trial is looking for
This trial is looking for adult patients with myelodysplastic syndromes (MDS) or similar conditions. Participants will have their bone marrow samples taken to study a specific type of cell death related to their condition.
Are You a Good Fit for This Trial?
You may be able to join if
- I am at least 18 years old
- I have been diagnosed with myelodysplastic syndromes
- I have ring sideroblasts in my bone marrow
- I can give my written consent
- I have social security coverage
You may not be able to join if
- I have received a blood transfusion in the last 120 days
- I have used hematopoietic growth factors in the last 30 days
- I have a condition affecting iron metabolism
- I am under legal protection or guardianship
- I am currently detained or imprisoned
- I cannot give consent
- I participated in another drug study in the last 30 days
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Myelodysplastic syndromes (MDS) are clonal diseases of hematopoietic stem cells (HSC) characterized by dysplastic and inefficient hematopoiesis related to excessive progenitor cell death. Ferroptosis is a recently described cell death mechanism and we think that it could be a major player in the pathophysiology of MDS, involved in the cell death that characterizes these diseases and contributing t…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
For all :
* Patients of legal age (age ≥ 18 years)
* Subjects affiliated to or benefiting from a social security scheme
* Free, written and informed consent signed by the participant and the investigator
For MDS patients :
* Sampling at diagnosis for MDS patients (WHO 2016 cr…
Contacts