Variations in Ketone Metabolism

Recruiting N/A Interventional Study
Ketosis
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
20 – 70
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
400 (estimated)
Sponsor
Ohio State University · Other
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About This Trial
This outcome of this study will elucidate how the phenotype of the individual modulates the KE metabolic effect. Most studies of KE have been in homogenous populations, usually young, male athletes. However, two striking experiments using identical, body weight adjusted KE doses in healthy and obese individuals found that BHB area under the curve (AUC) and removal was reduced by obesity and poor m…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Ages 20 - 70 years * Participant is willing and able to comply with all study procedures including the following prior to Test Day: fasting (\>10 h; water only), no alcohol (\>24 h), no exercise (\>24 h), no acute illness and controlled feeding before the Test Day, maintain di…
Contacts

Jeff Volek, PhD

6146881701

volek.1@osu.edu

CONTACT

Madison L Kackley, PhD

6142479650

kackley.19@osu.edu

CONTACT