POPular GUILTY PILOT: Genotype-guided Clopidogrel Monotherapy

Recruiting Phase 2 Interventional Study
Acute Coronary Syndrome CYP2C19 Polymorphism
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
200 (estimated)
Sponsor
St. Antonius Hospital · Other
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About This Trial
The goal of this pilot clinical trial is to test the safety and effectiveness of genotype-guided clopidogrel monotherapy in patients presenting with Non-ST-Segment Elevation Acute Coronary Syndrome (NSTE-ACS) who have undergone successful Percutaneous Coronary Intervention (PCI). The main questions it aims to answer are: * Is genotype-guided clopidogrel monotherapy effective in reducing ischemic …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: Patients aged 18 years or older are eligible for inclusion if all of the following criteria are met: * Clinical diagnosis of NSTE-ACS (i.e. NSTEMI or unstable angina) * Successful PCI (according to the treating physician) with implantation of new generation drug eluting stents.…
Contacts

Jaouad Azzahhafi, MD

+31883201321

j.azzahhafi@antoniusziekenhuis.nl

CONTACT

Jurrien ten Berg, MD PhD

+31883201321

j.ten.berg@antoniusziekenhuis.nl

CONTACT