No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
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At a Glance
Age
21 – 25
Sex
Any
Trial phase
Early Phase 1
Study type
Interventional
Purpose
Basic Science
Participants needed
250 (estimated)
Sponsor
Jessica Weafer · Other
Who this trial is looking for
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Answer a few quick questions to see if you may meet the eligibility requirements.
Findings from this project will determine the relationship between two vulnerability factors for Alcohol Use Disorder (AUD) in young adults: impulsivity and subjective response to alcohol. The results will identify badly needed, novel targets for prevention and treatment efforts to simultaneously reduce impulsivity and subjective responses in at-risk young adults.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 21-25 years old
* Report drinking to an estimated BAC \> .08% at least once in the past 30 days based on responses on the Timeline Followback (TLFB)
* Report drinking at least twice weekly in the past 30 days based on responses on the TLFB
* Fluency in English
Exclusion Crite…
Inclusion Criteria:
* 21-25 years old
* Report drinking to an estimated BAC \> .08% at least once in the past 30 days based on responses on the Timeline Followback (TLFB)
* Report drinking at least twice weekly in the past 30 days based on responses on the TLFB
* Fluency in English
Exclusion Criteria:
* Any serious medical problems (e.g., liver disease, cardiac abnormality, pancreatitis, diabetes, neurological problems, and gastrointestinal disorders)
* Body weight \< 110 or \> 210 pounds
* Axis I psychiatric disorders including substance use disorder other than mild or moderate alcohol or mild cannabis use disorder
* Current alcohol withdrawal or history of medically-assisted detoxification
* Two positive breath alcohol concentration (BrAC) readings (i.e., \> 0.00%) at an in-person screening appointment or experimental session
* Positive urine screen for illegal drugs other than cannabis
* Currently seeking or past-12-month history of inpatient or intensive treatment for addictive behaviors
* Current psychotropic medication use or receipt of a prescription for these medications in the past 30 days
* Psychosis or other psychiatric disability
* Pregnancy, nursing or lack of reliable birth control use for women
* Report smoking \> 5 cigarettes per day (to avoid acute nicotine effects or withdrawal during experimental sessions)
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