MRLinac Boost for Advanced Gynecological Cancers

MRLinac Boost for Gynecological Cancers if Brachytherapy is Not Feasible (MARGARITA)

Recruiting Observational Study
Cervical Cancer Gynecologic Cancer
No Study Drug Researchers observe your health over time — no experimental treatment is given.
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Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Female
Study type
Observational
Participants needed
30 (estimated)
Sponsor
UMC Utrecht · Other
Who this trial is looking for

This trial is looking for patients with advanced gynecological cancers who cannot receive a specific type of treatment called brachytherapy. Participants will receive a different type of radiation therapy and will be asked to fill out questionnaires about their experience.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have a biopsy-proven advanced stage gynecological cancer
  • I have a recurrent gynecological cancer and have not had prior radiation
  • I have para-aortic metastatic nodes (stage IVB) to the level of L2
  • I have given informed consent to take part in the MOMENTUM study

You may not be able to join if

  • I have a hard contraindication for MRI scanning

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial
The goal of this observational study is to explore the effectiveness and side effects of a high dose daily adapted SBRT (stereotactic body radiotherapy) boost delivered with MRLinac in patients with gynaecological cancers that cannot receive a brachytherapy boost to the primary tumour for different reasons (medical conditions, tumour extensions, etc). Current alternative for brachytherapy in these…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients with newly biopsy proven advanced stage gynecological cancers (excluding ovarian cancers) and endometrium in whom definitive (chemo)radiotherapy with curative intent is planned are qualified for the study, as well as, patients with recurrent gynecological cancers (exc…
Contacts

van Lier, PhD

+31 88 755 8800

a.l.h.m.w.vanlier@umcutrecht.nl

CONTACT