A Study to Assess Safety and Efficacy of CHO-H01 as a Single Agent/Combined With Lenalidomide in Subjects With Refractory or Relapsed Non-Hodgkin's Lymphoma

Recruiting Phase 1 Phase 2 Interventional Study
Non-Hodgkin Lymphoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 1/2
Study type
Interventional
Purpose
Treatment
Participants needed
37 (estimated)
Sponsor
Cho Pharma Inc. · Industry
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About This Trial
This is a 2-part study. Part 1/Phase 1 of the study will be conducted to determine the safety and tolerability of CHO-H01 in subjects with relapsed/refractory CD20+ non-Hodgkin's lymphoma. It will also determine maximum tolerated dose (MTD) and recommended phase II dose (RP2D). Part 2/Phase 2a will assess the anticancer activity and safety of CHO-H01 plus lenalidomide in subjects with low-grade r…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Life expectancy of \>12 weeks. * Body mass index of 18 to 32 kg/m2. * Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2. * Phase I: Have histologically (laboratory test) confirmed CD20 + non-Hodgkin's lymphoma according to the World Health Organization's 2…
Contacts

Tanny Tsao

886226558059

tanny.tsao@chopharma.com.tw

CONTACT