IVIM & OLINK in Sarcoma

Recruiting Phase 2 Interventional Study
Soft Tissue Sarcoma
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 100
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Diagnostic
Participants needed
145 (estimated)
Sponsor
University Health Network, Toronto · Other
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About This Trial
The hypoxia \> metastasis axis suggests that a DWI-based biomarker of hypoxia incorporating IVIM may be able to predict metastasis in STS patients, ultimately enabling stratification for personalized treatments at the time of diagnostic (MR) imaging, without adding an excessive burden to the patient or clinical workflow (typical DWI/IVIM sequences can be acquired acquired in approximately 5 minute…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years * Ability to understand and the willingness to sign a written informed consent document * Grade 2 or 3 soft tissue sarcoma greater than 5 cm in largest dimension Exclusion Criteria: * Contraindication to MRI scan as per current institutional guidelines (for pa…
Contacts

David Shultz, MD

416-946-4501

david.shultz@rmp.uhn.ca

CONTACT