IMA402 for Recurrent Solid Tumors

IMA402 T Cell-Engaging Receptor Molecule (TCER®) in Recurrent and/or Refractory Solid Tumors

Recruiting Phase 1 Phase 2 Interventional Study
Refractory Cancer Recurrent Cancer Solid Tumor, Adult Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 1/2
Study type
Interventional
Purpose
Treatment
Participants needed
400 (estimated)
Sponsor
Immatics Biotechnologies GmbH · Industry
Who this trial is looking for

This trial is looking for adult patients with certain types of solid tumors that keep coming back or don’t respond to treatment. Participants will take a new treatment called IMA402 to see how safe it is and if it helps shrink tumors.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am at least 18 years old
  • I have a confirmed advanced solid tumor
  • I have measurable disease according to RECIST criteria
  • I have a confirmed HLA status
  • My performance status is 0 or 1
  • My blood, liver, and kidney functions are normal

You may not be able to join if

  • I have other active cancers that need treatment
  • I am pregnant or breastfeeding
  • I have a history of severe allergies to IMA402 or its components
  • I have severe uncontrolled medical conditions
  • I have active brain metastases or a history of bleeding in brain metastases

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial
The goal of this clinical trial is to evaluate the safety, tolerability and anti-tumor activity of IMA402 in patients with recurrent and/or refractory solid tumors. Primary objectives: * To determine the maximum tolerated doses and/or recommended doses for extensions for IMA402 as monotherapy and in combination with pembrolizumab (Phase Ia) * To characterize the safety and tolerability of IMA402…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients ≥ 18 years old * Patients must have a specific pathologically confirmed and documented advanced and/or metastatic solid tumor indication * Patients must have received or not be eligible for indicated standard-of-care treatments per cohort * Measurable disease accordin…
Contacts

Immatics Biotechnologies GmbH

Please E-Mail

Ctgovinquiries@immatics.com

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